Endocrine Abstracts

Introduction: Vertebroplasty is a commonly performed technique in the management of vertebral compression fractures. However, it is associated with some serious adverse effects. Most complications are related to the leakage of bone cement (polymethylmethacrylate) into the spinal canal or the perivertebral venous system.Case report: A 74-year-old lady was subjected to percutaneous verterbroplasty for osteoporotic compression fractures on T11, T12, L1 and ...

Introduction: The description of a rare case of papillary thyroid cancer, neck paraganglioma, pituitary adenoma and Cowden-like syndrome.Case report: A 43-year-old woman presented with enlargement of her right thyroid lobe and a palpable ipsilateral neck mass. The pathology examination after operation of the two lesions revealed the synchronous presentation of a papillary thyroid carcinoma and a neck paraganglioma. Patient’s medical history included...

Introduction: Increased prevalence of thyroid autoimmunity has been described in few cases after successful treatment for Cushing’s syndrome. In De Quervain’s thyroiditis (DQT) autoimmunity does not seem to play a primary pathogenetic role.We describe two cases of DQT coinciding with the resolution of hypercortisolism, after successful treatment of Cushing’s syndrome/disease.Case 1: A 41-year-old female with Cushing&...

Introduction: VATER syndrome is a rare, usually sporadic, entity, including ≥2 of the following: vertebral defects (V), anal atresia (A), tracheoesophegeal fistula, esophageal atresia (TE) and radial or renal dysplasia (R).Maturity onset diabetes of youth (MODY) is a usually non-insulin-dependent type of monogenic diabetes mellitus (DM), usually in adults <25 years, with autosomal dominant inheritance, without the features of metabolic syndrome...

Introduction: Parathyroid cysts constitute a rare cause of primary hyperparathyroidism (PHPT). PHPT may also rarely coexist with non-medullary thyroid carcinoma (NMTC).Case presentation: A 70-year old woman was admitted to our department for type 2 diabetes mellitus (T2DM) management. She also reported nephritic colics due to kidney stone disease. There were no reports for fractures, symptoms of hypercalcemia or obstructive neck symptomatology. Laborator...

Background: Assessment of hypothalamic–pituitary adrenal axis in patients with schizophrenia is complex, as it involves both the disease process and antipsychotic medications. We present a case of a patient on long term clozapine with a concomitant pituitary adenoma who presented discordant responses to adrenal stimulation.Case: A 38-year old male was referred with chronic symptoms of reduced libido and associated low testosterone levels. He was tre...

Objective: Thyroid autoimmunity has been proposed as a risk factor for impaired health-related Quality of Life (HRQoL), depression and anxiety, though evidence is still limited. The aim of the current study is to assess the association of thyroid autoimmunity with quality of life in patients with benign thyroid disease.Design: A cross-sectional study was implemented, that included consecutive patients with benign thyroid diseases who visited the outpatie...

Introduction: Chest computed tomography imaging in patients with Covid-19 infection often reveals incidental adrenal lesions, which are subsequently investigated, after recession of the infection.Purpose: Description of a pheochromocytoma that was accidentally diagnosed in a teenager, during her hospitalization with Covid-19.Case description: A 17-year-old girl, who was diagnosed with covid-19 infection, by molecular testing 6 days...

Introduction: Various methods to quantify calcified coronary plaque have been used in common clinical practice in the past few decades to compliment cardiovascular risk assessment. The estimation of calcium load in other organs and conditions has been at best semi-quantitative. Patients with long-standing hypoparathyroidism are known to suffer with nephrocalcinosis and basal ganglia calcification. We attempted to quantify end-organ calcium burden in a series of patients with v...

Introduction: Adrenal ganglioneuroma (AGN) is a rare (about 470 described cases), benign tumor arising from the neural crest tissue. These tumors are usually asymptomatic and incidentally detected. They have variable radiological features that often raise suspicion of malignancy. AGN are diagnosed at a mean age of 50 years, have no gender preference and are rarely associated with genetic syndromes.Aim: The presentation of two male patients, 24 and 53 yea...